Fluorinated Alkyl Zinc Bromides in Cu/Photoredox Promoted Decarboxylative Cross‐Coupling

20260 citationsJournal Article

Authors

Sergey A. Imaev · Lomonosov Moscow State University

Anton A. Gladkov · Lomonosov Moscow State University

Vitalij V. Levin · N.D. Zelinsky Institute of Organic Chemistry

Alexander D. Dilman · N.D. Zelinsky Institute of Organic Chemistry

Abstract

The cross‐coupling of esters of N‐hydroxyphthalimide with fluorinated alkyl zinc reagents resulting in the C(sp 3 )−C(sp 3 ) bond formation is described. The method involves readily accessible perfluorinated and tetrafluorinated alkyl zinc bromides. The reaction is performed under copper and photoredox dual catalysis conditions.

Topics & Keywords

Fluorine in Organic Chemistry Radical Photochemical Reactions Catalytic C–H Functionalization Methods

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Advanced Synthesis & Catalysis

Volume 368, Issue 7

DOI: 10.1002/adsc.70389

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