Helminth coinfections mitigate clinical, parasitological, and immune outcomes in Mozambican children with malaria

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Authors

Inocência Cuamba · Departament de Salut

Rebeca Santano · Centro de Investigación en Red en Enfermedades Cardiovasculares

Berta Grau-Pujol · Departament de Salut

Marta Vidal · Barcelona Institute for Global Health

Ruth Aguilar · Barcelona Institute for Global Health

Anélsio Cossa · Manhiça Health Research Centre

Chenjerai Jairoce

Abstract

STH infections were associated with decreased P. falciparum parasitemia, downregulation of inflammatory cytokines, and enhanced antibody responses, potentially resulting in milder malaria episodes, suggesting enhanced protective immunity.

Topics & Keywords

Malaria Research and Control Parasites and Host Interactions Parasitic Diseases Research and Treatment

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: BMC Medicine

Volume 24, Issue 1

DOI: 10.1186/s12916-026-04827-7

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