AI-assessed sarcopenia as an independent predictor of neoadjuvant chemotherapy outcomes in muscle-invasive bladder cancer

Sarcopenia, assessed by AI-powered analysis, was negatively associated with tumor response following NAC in patients with MIBC. These findings support the integration of AI-driven sarcopenia evaluation into clinical staging workflows, enabling tailored nutritional interventions and improved patient stratification. Moreover, our study reinforces the prognostic value of the NacVI-RADS scoring system in predicting NAC outcomes.