Evaluating liver fibrosis in chronic hepatitis B patients using multi-compartment restriction spectrum imaging

The 4-compartment RSI model is a promising non-invasive tool for liver fibrosis staging. By resolving distinct diffusion and perfusion compartments, RSI overcomes key limitations of conventional DWI, with the C4 fraction (thought to reflect perfusion decline) serving as a sensitive biomarker for fibrosis progression and outperforming ADC in staging accuracy.