Selenium Protects Against Cadmium-Induced Hepatotoxicity via Regulation of Lipid Metabolism and Inflammatory Pathways

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Authors

Zilong Wu · Minzu University of China

Xinyi Chen · The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture

Xiaoying Pan · Minzu University of China

Kai Luo · Minzu University of China

Zixiong Zhang · The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture

Changyu Zhou · The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture

Huimin Wang

Abstract

Se confers hepatoprotection against Cd toxicity not only through its classical antioxidant activity but also through coordinated modulation of lipid metabolic pathways and inflammatory signaling. This study provides mechanistic insights into Se-mediated defense against Cd-induced hepatotoxicity and highlights the therapeutic potential of Se-enriched phytochemicals for mitigating the adverse effects of environmental Cd exposure.

Topics & Keywords

Heavy Metal Exposure and Toxicity Saffron Plant Research Studies Antioxidants, Aging, Portulaca oleracea

Publication Details

Published in: Frontiers in Bioscience-Landmark

Volume 31, Issue 3, pp. 50288-50288

DOI: 10.31083/fbl50288

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Selenium Protects Against Cadmium-Induced Hepatotoxicity via Regulation of Lipid Metabolism and Inflammatory Pathways

Authors

Abstract

Topics & Keywords

Publication Details