Healthcare resource utilization comparing single-use ureteroscopes with real-time intrarenal pressure monitoring to other single-use ureteroscopes

Introduction: This study compared post-procedure healthcare resource utilization with LithoVue™ Elite (LVE) single-use digital flexible ureteroscope with pressure monitoring vs. other (non-pressure sensing) single-use ureteroscopes. Methods: This retrospective, real-world study used the Premier PINC AI™ Healthcare Database. Adults aged 18+ undergoing ureteroscopy (URS) with lithotripsy between January 1,2024 and March 1, 2025, with ≥30-day post-URS followup were included. The primary outcomes were 10- and 30-day hospital resource utilization (HRU), a composite measure of emergency department (ED) visits or inpatient admission. Propensity score matching (1:3) balanced baseline characteristics. Multivariable logistic regression in the matched cohort adjusted for residual confounding. Results: A total of 305 patients underwent LVE with pressure monitoring capability (mean [standard deviation (SD)] age 58.6 [16.1], 51.1% female) and 15 048 underwent other single-use ureteroscopes (mean [SD] age 58.7 [15.8], 51.7% female). After matching, 292 LVE patients were compared with 876 controls. Patients undergoing LVE with pressure monitoring capability experienced improved HRU outcomes at 10-day (4.5% vs. 8.7%; ARR 4.2 pp, p=0.016) and 30-day (7.2% vs. 12.0%; ARR 4.8 pp, p=0.019) vs. other single-use ureteroscopes. In adjusted analyses, LVE with pressure monitoring capability was associated with lower odds of HRU at 10-day (odds ratio [OR] 0.355, 95% confidence interval [CI] 0.175-0.718, p=0.004) and 30-day (OR 0.473, 95% CI 0.281-0.797, p=0.005). The odds of 10-day ED visits (OR 0.385, 95% CI 0.149-0.997, p=0.049) and 30-day inpatient admissions (OR 0.436, 95% CI 0.196-0.967, p=0.041) were significantly lower with LVE with pressure monitoring capability. Conclusions: Use of LVE with pressure monitoring capability was associated with clinically meaningful reductions in early post-URS HRU vs. other single-use ureteroscopes.