Combating orthopedic implant biofilms — SABER (Study on Agitation for Biofilm Eradication and Reduction) evaluates mechanical, sonication, and radiofrequency approaches: a preclinical in vitro study

Our data shows consistent qualitative and quantitative reduction in biofilm burden with brushing interventions compared with irrigation and control. While further study is warranted, our data suggest that mechanical brushing with sonication and radiofrequency may be beneficial tools in reducing biofilm burden on orthopedic metal implants.