Prognostic value of Ki67 and PSA-immunostaining in <i>de novo</i> metastatic hormone-sensitive prostate cancer

20260 citationsJournal Articlegold Open Access

Authors

Ana Marta Ferreira · Hospitais da Universidade de Coimbra

Roberto Jarimba · Hospitais da Universidade de Coimbra

A. Cristina Rego · Hospitais da Universidade de Coimbra

João Martins Gama · Hospitais da Universidade de Coimbra

Rui Manuel S. de Almeida · Pathological Society

Miguel Eliseu · Hospitais da Universidade de Coimbra

Vasco Quaresma

Abstract

Combined Ki67 and PSA-IHC assessment refines risk stratification in de novo mHSPC, identifying a high-risk PSA-IHC low/Ki67 high subgroup with markedly worse prognosis. These findings warrant prospective validation.

Topics & Keywords

Prostate Cancer Treatment and Research Prostate Cancer Diagnosis and Treatment Radiopharmaceutical Chemistry and Applications

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Archivio Italiano di Urologia e Andrologia

Volume 98, Issue 1, pp. 14731-14731

DOI: 10.4081/aiua.2026.14731

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