Lower Allele Frequency of <i>TERT</i> -rs2242652 in Sub-Saharan African Populations Compared With American Populations and Hepatocellular Carcinoma Risk

In sub-Saharan African populations, there was a lower frequency of the HCC protective allele <i>TERT</i>-rs2242652 compared with European Americans. These findings underscore the importance of multiethnic genetic studies in understanding population differences in HCC risk and developing prevention strategies.