Friend of GATA2 Variant Ser657Gly Is Associated With Coronary Microvascular Disease

20260 citationsJournal Articlehybrid Open Access

Authors

Marie Guerraty · University of Pennsylvania

S. Shefali Verma · University of Pennsylvania

Yi-An Ko · Maine Farmland Trust

Michael A. McQuillan · Maine Farmland Trust

Donna Conlon · University of Pennsylvania

John W. Tobias · Institut thématique Génétique, génomique et bioinformatique

Michael G. Levin

Abstract

A common functional coding variant in FOG2, S657G, is associated with CMVD in humans. Altered angiogenic gene expression, regulated in part by FOG2, may contribute to CMVD.

Topics & Keywords

Congenital heart defects research Diabetes and associated disorders Genomic variations and chromosomal abnormalities

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Genomic and Precision Medicine

DOI: 10.1161/circgen.125.005342

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