Antibiotic Profile of Pseudomonas aeruginosa in a Tertiary Care Hospital

Pseudomonas aeruginosa is an important opportunistic pathogen responsible for both hospital-acquired and community-acquired infections. Its intrinsic and acquired resistance to multiple antibiotics poses significant therapeutic challenges. This study aimed to evaluate the prevalence and antibiogram of P. aeruginosa isolates in a tertiary care hospital. A total of 503 clinical samples were processed, out of which 32 isolates of P. aeruginosa were identified, giving a prevalence rate of 6.38%. Antibiotic susceptibility testing revealed variable resistance patterns, with all isolates remaining sensitive to colistin. A considerable proportion (27%) of isolates were multidrug-resistant. Continuous surveillance and rational antibiotic use are essential to control infections caused by this organism.