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To investigate how knee joint protector design affects the biomechanical characteristics of knee motion under various activities, this pilot study (n = 5) examined how knee joint protector design modulates knee biomechanics across walking, jogging, squatting, and sit-to-stand tasks using optical motion capture and AnyBody musculoskeletal modeling (FullBody_GRFPrediction). We quantified knee flexion kinematics, model-estimated joint reaction forces and moments, and model-estimated muscle activity of eight lower-limb muscles under four conditions with different levels of structural constraint: no protector (Pro.off), a conventional sleeve-type protector (Pro.a), a segmented support protector (Pro.b), and a wrapping fixation protector (Pro.c). The biomechanical protective performance of the knee joint protector was task- and phase-dependent. The results showed that Pro.a optimized muscle activation. Pro.b increased sagittal-plane design but increased joint loading and muscle activity. Pro.c induced noticeable distal compensation along the kinetic chain. The findings revealed that protector effects were task-dependent. Dynamic tasks mainly affected coronal-plane stability parameters, whereas quasi-static tasks more clearly altered sagittal load distribution. In this study, biomechanical protective performance is defined as reduced knee joint loading without disproportionate increases in model-estimated muscle activity or excessive loss of functional knee flexion range. Under this definition, greater structural constraint did not consistently produce a more favorable biomechanical profile. These results provide a feasibility baseline for task-specific protector evaluation and motivate confirmatory studies with larger cohorts and experimental validation. This study provides theoretical and methodological insights to guide future design and optimization of knee joint protectors.