GLP-1 Receptor Agonists and Noncardiometabolic Outcomes

20260 citationsJournal Articlegold Open Access

Authors

Kehu Yang · National Health and Family Planning Commission

Changyuan Liu · National Health and Family Planning Commission

Yongze Li · National Health and Family Planning Commission

Abstract

In this umbrella review of meta-analyses, evidence for most noncardiometabolic outcomes associated with GLP-1 RAs was of lower certainty. Potential safety signals were observed for gastrointestinal AEs, while suggested protective associations with respiratory diseases and serious infections require further confirmation.

Topics & Keywords

Diabetes Treatment and Management Hyperglycemia and glycemic control in critically ill and hospitalized patients Gastroesophageal reflux and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Network Open

Volume 9, Issue 3, pp. e264722-e264722

DOI: 10.1001/jamanetworkopen.2026.4722

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