Sammulfar pharmacological uses and toxicological effect on systemic organs a revive studies

Sammulfar (Arsenic) is a versatile mineral. It is inorganic and organic compound, it belongs to group VA of the periodic table, arsenic is an anti-leukemic agent. In the form of sodium arsenite solution it was the first effective systemic chemotherapy for a neoplastic disease reported by Lissauer. The "arsenic" utilized by criminals and murderers is typically the trioxide form As2O3, also known as "white arsenic" or the mineral arsenolite, arsenic compounds are classified into three major groups based on their biology and toxicology like Inorganic arsenic compounds, organic arsenic compounds, Arsenic gas. It is used in Unani system of medicine pharmacological actions and therapeutic uses, many important Unani formulations like Kusta Sammulfar, Habb-e-Ahmar Tila-e-Ajeeb etc its temperament (Mizaj) garam khusk 4°. It is toxic element, arsenic have found acute and chronic toxicity effect on systemic organ likes immune system, skin, hepatic portal system, cardiovascular system, gastrointestinal system, neurological system, genitourinary system, respiratory system etc.