Research progress on the prevention and treatment of exercise-induced fatigue with ginseng and relevant formulas

In recent years, numerous studies have confirmed that ginseng and ginseng-containing formulas exert significant preventive and therapeutic effects on exercise-induced fatigue (EIF). Their anti-fatigue effects are mainly mediated by regulating neurotransmitter release, modulating cytokine receptor binding, and interfering with cell adhesion molecule interactions. This review systematically analyzes and discusses the research progress of ginseng and ginseng-containing formulas in EIF management from the perspectives of formula composition, pharmacological mechanism, and clinical application, with the aim of providing a theoretical basis for syndrome differentiation-based treatment and precise clinical medication of EIF.