Modern Features of the Epizootiological and Epidemiological Situation on Hemorrhagic Fever with Renal Syndrome in the Rostov Region

The wide spread of hantavirus infection with a tendency to a constant increase in the number of cases is an urgent concern of practical healthcare worldwide. The aim of the work was to analyze the features of the epizootiological and epidemiological situation on hemorrhagic fever with renal syndrome in the Rostov Region. Materials and methods. Epizootiological monitoring in 2023–2024 was carried out in 23 administrative territories of the Rostov Region. 1202 specimens of 14 small mammal species were examined for the presence of orthohantavirus markers: in 2023 – 755, in 2024 – 447. The stratum of the local population that is immune to orthohantaviruses was identified using ELISA. Results and discussion. Throughout the study, hantavirus markers were detected in seven administrative territories of the region: Krasnosulinsky, Millerovsky, Kamensky, Bagaevsky, Azovsky, Orlovsky districts and the vicinity of Rostov-on-Don, in populations of six rodent species: house mouse, small white-toothed mouse, small forest mouse, field vole, social vole, gray rat. Screening study of blood sera from individuals who had not had HFRS before showed the presence of class G immunoglobulins in 2023 – 18.6 %, in 2024 – 3.3 %. Regular findings of orthohantavirus markers in populations of small mammals and the annual detection of seropositive samples among the conditionally healthy population confirm the existence of a polyhostal natural focus and indicate the population contacts with components of the parasitic system.