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Cancer is a complex global disease, and breast cancer is one of its most prevalent forms. Breast cancer showcases a remarkable degree of heterogeneity. Modern medicine has been used as the primary form of care with several modalities. Despite substantial strides in medical research and therapeutic innovations, the complicated nature of breast cancer poses enduring challenges in achieving universally optimal outcomes, such as resistance mechanisms, tumor recurrence dynamics, and the insidious progression of metastatic disease, underscoring the imperative for continued exploration and innovation in breast cancer management. In parallel, traditional herbal medicine, deeply rooted in Asian cultures and practices, has garnered attention as a complementary and alternative therapeutic domain, offering a reservoir of bioactive compounds with potential anticancer properties. Within this context, herbal remedies have historically played a pivotal role in developing antitumor agents, leveraging their innate ability to modulate cellular pathways, counter oxidative stress, and impede carcinogenic processes triggered by free radicals. Such botanical interventions present a holistic approach to cancer prevention and treatment, emphasizing the therapeutic potential of plant-derived compounds and their preventive capabilities against disease initiation and progression. This review explores the scientific basis of four frequently used Asian herbs, focusing on their pharmacological activities and clinical evidence for efficacy in reducing chemotherapy toxicity and supporting breast cancer management. In addition, this review also illuminates the prophylactic properties of these four Asian herbs as cancer-preventive agents.
Published in: Current Bioactive Compounds
Volume 22, Issue 5