Cooley's Legacy Endures—Elliptocytes in X‐Linked Sideroblastic Anemia due to Aminolevulinate Synthase 2 Mutations

20260 citationsJournal Article

Authors

Alex Ciurej · Children's Hospital of Michigan

Süreyya Savaşan · Central Michigan University

Kanta Bhambhani · Central Michigan University

Manisha Gadgeel · Children's Hospital of Michigan

Madhvi Rajpurkar · Central Michigan University

Yaddanapudi Ravindranath · Wayne State University

Abstract

ABSTRACT X‐linked sideroblastic anemia (XLSA) is categorized as hypochromic microcytic anemia. In 3 children with XLSA, we observed prominent elliptocytosis, and red cell band 3 content histograms were similar to those found in hereditary elliptocytosis, thus validating Cooley's descriptions in 1945.

Topics & Keywords

Porphyrin Metabolism and Disorders Metabolism and Genetic Disorders Erythrocyte Function and Pathophysiology

Publication Details

Published in: Pediatric Blood & Cancer

DOI: 10.1002/1545-5017.70313

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Cooley's Legacy Endures—Elliptocytes in X‐Linked Sideroblastic Anemia due to Aminolevulinate Synthase 2 Mutations

Authors

Abstract

Topics & Keywords

Publication Details