Determination of the Simultaneous Hepatoprotective and Antidepressant Activity of the Composition Hepalipin and Yantacin

Although only a few groups of drugs with hepatoprotective activity are recognized, the introduction of drugs with high liver protective activity, mainly based on natural compounds or plants, has become an urgent problem especially, over the last twenty years. A striking example of this is the fact that the hepatoprotective activity of existing phytotherapeutic drugs is not as high as that of synthetic drugs. However, secondary plant metabolites, including flavonoids, flavones, flavonols, and other naturally occurring biologically active compounds, are becoming a promising therapeutic alternative to traditional medicines in modern medicine. The priority purpose of this study is to introduce a new highly hepatoprotective and at the same time biologically active antidepressant of a new composition based on a combination of phospholipid, lycopene, glycerisic acid and yantacin obtained from plants. All of the research was done on rats, and the administration of heliothrin, a chemical that has a hepatotoxic effect, into the abdominal cavity in accordance with a rigorous plan resulted in significant chronic liver damage. Its hepatoprotector and antidepressant properties were compared to those of the well-known medication Phosphogliv and fluoxetine, which are both commonly used in medicine. The study's focus was a 1:1 mixture of heparin and yanatacin. As a result, the pharmacological composition that is being presented is completely safe, and research has shown that its constituents exhibit a markedly elevated activity not only in relation to the well-known medication phosphogliv, but also in relation to the ecdysteroid form of yantacin and hepalipin. Consequently, the pharmacological composition offered is entirely safe, and studies have demonstrated that its components have significantly higher activity not only when compared to the well-known drug phosphogliv, but also when compared to the ecdystenic form of yantacin and hepalipin.