Multivitamins and Polyunsaturated Fatty Acids in the Treatment of Dry Eye Syndrome

Dry eye syndrome is a global problem of the modern world. Overload of information, rapid urbanization, and a busy lifestyle lead to non-compliance with work and rest schedules, including increased visual loads, decreased stress resistance in conditions of time deficit, leading to a deficiency of vital substances in the body. All the above are risk factors for the development of dry eye syndrome and affect the course of this disease. It is a well-known fact that balanced nutrition, regular intake of vitamins and microelements with food, and compliance with work and rest schedules play a role in the prevention and elimination of clinical manifestations of these conditions. This article presents the results of using the biologically active food supplement “DOPPELHERZ® V.I.P. OFTALMOVIT No. 30” (manufacturer Queisser Pharma GmbH & Co. KG, Germany) in the treatment of dry eye syndrome. The purpose of the study: to evaluate the effect of the dietary supplement “DOPPELHERZ® V.I.P. OFTALMOVIT no. 30” in the treatment of dry eye syndrome. Material and methods. The study included 90 students with dry eye syndrome, aged 18 to 26 years. Patients of group I (control) did not receive any dietary supplements; group II (study group) received the dietary supplement “DOPPELHERZ® V.I.P. OFTALMOVIT”. Results. OSDI questionnaire — in the study group, the severity of dry eye syndrome: “before” moderate n = 38, severe n = 22, “1 month” moderate n = 43, severe n = 17, “2 months” mild n = 11, moderate n = 43, severe n = 6, in the control group no changes ( p = 0.368). Norn’s test: the study group showed an increase in tear film breakup time ( p < 0.001), no changes were recorded in the control group ( p = 0.285). Lacrimal meniscus height: the study group showed an increase in the height of the lacrimal meniscus, which indicates an improvement in the functional properties of the tear film and a decrease in dry eye syndrome ( p < 0.001), no changes were recorded in the control group ( p = 0.105). Schirmer tests 1 and 2: the study group showed an increase in the tear film breakup time, which indicates an improvement in the functional properties of the tear film and a decrease in dry eye syndrome, no changes were recorded in the control group (RSH1 = 0.587, RSH2 = 0.293). CISS questionnaire: a gradual decrease in the severity of asthenopia signs was observed in the study group ( p < 0.001), no changes were recorded in the control group ( p = 0.125). Pupillography: in the study group, regression of accommodation tension was recorded, more pronounced after 2 months ( p < 0.001), in the control group there was a change in accommodation tension, which can be associated with the alternating predominance of sympathetic and parasympathetic wagging ( p < 0.05). Discussion. The concept of dry eye syndrome treatment includes etiopathogenetic, non-specific and symptomatic therapy. An integral link in the strategy of pathogenetic treatment of dry eye syndrome is the targeted introduction of vitamins and microelements into the diet. Conclusion. Based on the results of the study, as well as on the data of foreign and domestic authors, dietary supplements can serve as an additional source of vitamins and microelements, the deficiency of which is one of the components of the causes of dry eye syndrome pathogenesis. Considering the above, we can recommend taking the dietary supplement “DOPPELHERTS ® V.I.P. OFTALMOVIT” 1 capsule once a day for 2 months in the complex therapy of patients with dry eye syndrome.