Modern approaches to risk stratification and prognosis assessment in patients with pulmonary arterial hypertension

Pulmonary arterial hypertension is a severe progressive disease with a high mortality risk, requiring an accurate prognosis assessment to optimize therapy. Risk stratification plays a key role in predicting survival and choosing treatment tactics. Modern approaches in risk stratification are based on an integrated assessment of clinical, hemodynamic, laboratory and instrumental parameters to identify patients with low, intermediate and high risk of death within 1 year, which allows to personalize treatment: from monotherapy to aggressive combination regimens and referral for transplantation.