Selective hemoadsorption of cytokines and platelet-neutrophil complexes mitigates lung microvascular hyperpermeability in an ovine acute lung injury model

Simultaneous removal of cytokines and PNCs using NOA-001 significantly reduced ARDS severity by attenuating pulmonary edema and improving pulmonary gas exchange. These results suggest that NOA-001 may be a novel and promising therapeutic strategy for ARDS.