Additional file 1 of Tadehagi triquetrum aqueous extract ameliorates diabetic kidney disease through mitigating epithelial senescence via the PTEN/AKT/mTOR signaling pathway

Supplementary Material 1.Fig S1. A–D Water intake and food intake during the administration period. E-H The urinary ACR (E), blood urea nitrogen (F), serum creatinine (G), and urinary β2-MG (H) levels were measured using commercial kits (n = 6 per group). I Masson staining of kidney tissues. Scale bar = 100 μm. Data are presented as the means ± SEM. ###P < 0.001 vs. Control group; ^P < 0.05 vs. DKD group. Fig S2. A Cell aiablity of HK2 after TAE treatment. B mRNA level of PTEN. C Protein level detected by Western blot analysis (n = 3 per group)