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Nanoscale direct-to-biology optimization of Cdk2 inhibitors

20260 citationsJournal Article

Authors

James L. Douthwaite · University of Michigan

Damian J. Houde · Relay Therapeutics (United States)

Eneida Pardo · Relay Therapeutics (United States)

Mark Moran · Relay Therapeutics (United States)

Jason R. Baird · Relay Therapeutics (United States)

Sophia R. Meyer · University of Michigan

Topics & Keywords

Cancer-related Molecular Pathways Cancer Mechanisms and Therapy Peptidase Inhibition and Analysis

Publication Details

Published in: ChemRxiv

DOI: 10.26434/chemrxiv-2025-4fr3l/v2

Field-Weighted Citation Impact: 0.00

Nanoscale direct-to-biology optimization of Cdk2 inhibitors | Researchclopedia

· University of Michigan

Q. Zhao · University of Michigan

Jay F. Larrow · Relay Therapeutics (United States)

Yu-Pu Juang · University of Michigan

Calvin Han · Relay Therapeutics (United States)

Brian D. Kelley · Relay Therapeutics (United States)

David R. Dunstan · Relay Therapeutics (United States)

Katelyn Billings · Relay Therapeutics (United States)

Mary M. Mader · Relay Therapeutics (United States)

Alexander Merton Taylor · Relay Therapeutics (United States)

Jonathan Z. Sexton · University of Michigan

Alessandro A. Boezio · Relay Therapeutics (United States)

Tim Cernak · University of Michigan