Decoding Sickle Cell Disorders Using Flow Injection Analysis Mass Spectrometry

20260 citationsJournal Article

Authors

Deepalakshmi D. Putchen · Directorate of Medicinal and Aromatic Plants Research

Ankitha K. Puthiyaveettil · Directorate of Medicinal and Aromatic Plants Research

Swathi Kulkarni · Directorate of Medicinal and Aromatic Plants Research

Pradeep Kumar Venkatachala · Directorate of Medicinal and Aromatic Plants Research

Sujay Ramaprasad · Directorate of Medicinal and Aromatic Plants Research

Abstract

A rapid, cost-effective MS approach distinguishes SCT from SCD while γ/β and δ/α (%), ratios refine SCD subclassification alongside β<sup>S</sup>/β. Combined with capillary electrophoresis (CE), this approach enhances diagnostic resolution and may reduce the need for molecular testing.

Topics & Keywords

Hemoglobinopathies and Related Disorders Metabolomics and Mass Spectrometry Studies Microfluidic and Capillary Electrophoresis Applications

Publication Details

Published in: Rapid Communications in Mass Spectrometry

Volume 40, Issue 12, pp. e70067-e70067

DOI: 10.1002/rcm.70067

Field-Weighted Citation Impact: 0.00

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Decoding Sickle Cell Disorders Using Flow Injection Analysis Mass Spectrometry

Authors

Abstract

Topics & Keywords

Publication Details