PLGA‐particle‐based vaccine induces SARS‐CoV‐2‐specific antibody and T‐cell responses

20260 citationsJournal Articlehybrid Open Access

Authors

Dennis J. Horvath · University of Konstanz

Katharina Inholz · University of Konstanz

Dennis Mink · University of Konstanz

Alicia Madel · University of Konstanz

Julia Koerner · University of Konstanz

Reinhold Horlacher · University of Konstanz

Michael Basler ·

Abstract

PLGA microparticle-based vaccination induces potent systemic and mucosal immune responses against SARS-CoV-2 RBD. This adaptable platform represents a promising approach for mucosal vaccination strategies, with potential for rapid adaptation to emerging variants.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research Immunotherapy and Immune Responses vaccines and immunoinformatics approaches

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: British Journal of Pharmacology

DOI: 10.1111/bph.70423

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