A Systematic Review and Meta-analysis of Externally Validated Epic Clinical Decision Support Tools

20260 citationsJournal Articlehybrid Open Access

Authors

Hardik Patel · Northwell Health

Salvatore Crusco · Northwell Health

Derek Hansen · Northwell Health

Jaclyn Morales · Northwell Health

Tara Patale · Northwell Health

Codruța Chiuzan · Northwell Health

Mark Sands · Northwell Health

Abstract

Epic's CDS tools demonstrated modest real-world performance, with none exceeding AUROC 0.79. Three models (ESM, EURM, EEOL-CI) underperformed Epic's reported ranges. High heterogeneity across sites emphasizes the need for local validation before clinical deployment.

Topics & Keywords

Electronic Health Records Systems Sepsis Diagnosis and Treatment Health Systems, Economic Evaluations, Quality of Life

UN Sustainable Development Goals

Peace, Justice and strong institutions

Publication Details

Published in: Journal of General Internal Medicine

DOI: 10.1007/s11606-026-10381-y

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