Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

20151,256 citationsJournal Articlebronze Open Access

Authors

Peter Lange · Universidad Autónoma de Madrid

Bartolomé R. Celli · Brigham and Women's Hospital

Àlvar Agustí · Centro de Investigación Biomédica en Red de Enfermedades Respiratorias

Gorm Boje Jensen · Frederiksberg Hospital

Miguel Divo · Harvard University

Rosa Faner · Centro de Investigación Biomédica en Red de Enfermedades Respiratorias

Stefano Guerra

Abstract

Our study suggests that low FEV1 in early adulthood is important in the genesis of COPD and that accelerated decline in FEV1 is not an obligate feature of COPD. (Funded by an unrestricted grant from GlaxoSmithKline and others.).

Topics & Keywords

Chronic Obstructive Pulmonary Disease (COPD) Research Respiratory Support and Mechanisms Asthma and respiratory diseases

Publication Details

Published in: New England Journal of Medicine

Volume 373, Issue 2, pp. 111-122

DOI: 10.1056/nejmoa1411532

Field-Weighted Citation Impact: 79.64

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Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

Authors

Abstract

Topics & Keywords

Publication Details