SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis

2015127 citationsJournal Articlehybrid Open Access

Authors

Q. Zhang · University of Liverpool

Quanbo Ji · People's Liberation Army No. 150 Hospital

X. Wang · People's Liberation Army No. 150 Hospital

Lei Kang · Peking University

Ying Fu · People's Liberation Army No. 150 Hospital

Yuhua Yin · People's Liberation Army No. 150 Hospital

Z. Li

Abstract

These findings indicated that SOX9 upregulation might mediate ADAMTSs suppression at the early stage of human OA. In addition, SOX9 could be used as a potential therapeutic agent for human OA at an early stage.

Topics & Keywords

Osteoarthritis Treatment and Mechanisms Inflammatory mediators and NSAID effects Chemokine receptors and signaling

Publication Details

Published in: Osteoarthritis and Cartilage

Volume 23, Issue 12, pp. 2259-2268

DOI: 10.1016/j.joca.2015.06.014

Field-Weighted Citation Impact: 4.83

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SOX9 is a regulator of ADAMTSs-induced cartilage degeneration at the early stage of human osteoarthritis

Authors

Abstract

Topics & Keywords

Publication Details