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Luke Ames | Researchclopedia

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Luke Ames

University of Birmingham ORCID

16

Works

142

Citations

6

h-index

5

i10-index

Research Topics

Acute Myeloid Leukemia Research Genomics and Chromatin Dynamics Protein Degradation and Inhibitors

Affiliations

University College Birmingham2025–2025

Cancer Research UK Clinical Trials Unit2022–2022

University of Birmingham2019–2026

Top Works

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

Anetta Ptasinska,Anna Pickin,et al.

201936 citations

Epigenetics and DNA Methylation

Histone Deacetylase Inhibitors Research

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth

Sophie G. Kellaway,Sandeep Potluri,et al.

202430 citations

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification

Benjamin Edginton‐White,Alexander Maytum,et al.

202325 citations

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

Assunta Adamo,Paulynn Suyin Chin,et al.

202219 citations

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

Daniel Coleman,Peter Keane,et al.

202312 citations

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

Daniel Coleman,Peter Keane,et al.

20249 citations

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

Daniel Coleman,Peter Keane,et al.

20234 citations

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

Anetta Ptasinska,Anna Pickin,et al.

20194 citations

Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth

Sophie G. Kellaway,Sandeep Potluri,et al.

20232 citations