Researchclopedia

Research Researchers Institutions Topics Submit About

Command Palette

Search for a command to run...

Researchclopedia

Research Researchers Institutions About

© 2026 Researchclopedia. Powered by OpenAlex under CC0 license.

P. Marchot | Researchclopedia

Back to researchers

P. Marchot

Centre National de la Recherche Scientifique ORCID

204

Works

6,515

Citations

43

h-index

96

i10-index

Research Topics

Cholinesterase and Neurodegenerative Diseases Nicotinic Acetylcholine Receptors Study Computational Drug Discovery Methods

Affiliations

Roche (Switzerland)1999–2010

Centre National de la Recherche Scientifique1987–2026

Mayo Clinic1998–1998

Howard Hughes Medical Institute2002–2002

Inserm1987–1989

Top Works

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

Scott B. Hansen,Gerlind Sulzenbacher,et al.

2005628 citations

Ion channel regulation and function

Venomous Animal Envenomation and Studies

Acetylcholinesterase inhibition by fasciculin: Crystal structure of the complex

Yves Bourne,Palmer Taylor,et al.

1995352 citations

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

Yves Bourne,Hartmuth C. Kolb,et al.

2004329 citations

ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions

Nicolas Lenfant,Thierry Hôtelier,et al.

2012328 citations

Crystal structure of a Cbtx–AChBP complex reveals essential interactions between snake α‐neurotoxins and nicotinic receptors

Yves Bourne,Todd T. Talley,et al.

2005307 citations

Immunocytochemical Localization and Crystal Structure of Human Frequenin (Neuronal Calcium Sensor 1)

Yves Bourne,Jens Dannenberg,et al.

2001177 citations

Conformational Flexibility of the Acetylcholinesterase Tetramer Suggested by X-ray Crystallography

Yves Bourne,Jacques Grassi,et al.

1999175 citations

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor

Ryan Hibbs,Gerlind Sulzenbacher,et al.

2009163 citations

Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism

Yves Bourne,Zoran Radić,et al.

2010157 citations