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James A. Milligan | Researchclopedia

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James A. Milligan

Royal North Shore Hospital ORCID

32

Works

3,711

Citations

22

h-index

26

i10-index

Research Topics

Sphingolipid Metabolism and Signaling Lipid Membrane Structure and Behavior Carbohydrate Chemistry and Synthesis

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)1988–2017

Royal North Shore Hospital2025–2025

The Royal Free Hospital1973–1973

NKT Therapeutics (United States)2025–2025

Center for Rheumatology2002–2002

Top Works

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

Suzanne Mandala,Richard Hajdu,et al.

20021,677 citations

Antifungal resistance and susceptibility

Receptor Mechanisms and Signaling

Immune Cell Regulation and Cardiovascular Effects of Sphingosine 1-Phosphate Receptor Agonists in Rodents Are Mediated via Distinct Receptor Subtypes

M J Forrest,S.-Y. Sun,et al.

2004333 citations

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

Robert W. Myers,Hong-Ping Guan,et al.

2017332 citations

Khafrefungin, a Novel Inhibitor of Sphingolipid Synthesis

Suzanne Mandala,Rosemary Thornton,et al.

1997137 citations

Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies

Martha Kurtz,George K. Abruzzo,et al.

1996137 citations

Rustmicin, a Potent Antifungal Agent, Inhibits Sphingolipid Synthesis at Inositol Phosphoceramide Synthase

Suzanne Mandala,Rosemary Thornton,et al.

1998120 citations

Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (S1P<sub>1</sub>) Receptor Agonists with Exceptional Selectivity against S1P<sub>2</sub> and S1P<sub>3</sub>

Zhen Li,Weirong Chen,et al.

200599 citations

A Rational Utilization of High-Throughput Screening Affords Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists

Jeffrey J. Hale,Christopher L. Lynch,et al.

200488 citations

Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720

Jeffrey J. Hale,William Neway,et al.

200473 citations