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Tyler Jacks | Researchclopedia

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Tyler Jacks

Howard Hughes Medical Institute ORCID

816

Works

125,655

Citations

158

h-index

353

i10-index

Research Topics

Cancer-related Molecular Pathways Cancer Research and Treatments Cancer Genomics and Diagnostics

Affiliations

Broad Institute2006–2021

Ontario Institute for Cancer Research2010–2010

University of North Carolina at Chapel Hill1992–1992

Tufts University1998–2011

Brigham and Women's Hospital2003–2020

Top Works

MicroRNA expression profiles classify human cancers

Jun Lü,Gad Getz,et al.

20059,549 citations

RNA modifications and cancer

Chromatin Remodeling and Cancer

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Mitchell Guttman,Ido Amit,et al.

20094,170 citations

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie,Pablo Tamayo,et al.

20094,120 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan,Qimin Zhan,et al.

19923,084 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

Scott W. Lowe,H. Earl Ruley,et al.

19932,940 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

Scott W. Lowe,Earlene M. Schmitt,et al.

19932,886 citations

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani,Emanuel F. Petricoin,et al.

20032,463 citations

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber,Cynthia Osmanian,et al.

19962,311 citations

Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer

Carla F. Bender Kim,Erica L. Jackson,et al.

20052,194 citations