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Jayne Chin | Researchclopedia

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Jayne Chin

Roche (Switzerland)

30

Works

5,595

Citations

26

h-index

28

i10-index

Research Topics

Immune Response and Inflammation Monoclonal and Polyclonal Antibodies Research Glycosylation and Glycoproteins Research

Affiliations

Roche (Switzerland)2013–2013

Merck & Co., Inc., Rahway, NJ, USA (United States)1986–2012

Harvard University1995–1995

Hospital of the University of Pennsylvania1986–1986

Massachusetts General Hospital1995–1995

Top Works

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry,Herbert G. Bull,et al.

19922,560 citations

Cholesterol and Lipid Metabolism

RNA and protein synthesis mechanisms

Identification of a monocyte specific pre-interleukin 1 beta convertase activity.

Matthew J. Kostura,Michael J. Tocci,et al.

1989510 citations

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

Caterina Missero,Enzo Calautti,et al.

1995335 citations

The interleukin‐1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function

Johanne Martel‐Pelletier,Robert W. McCollum,et al.

1992188 citations

CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells

Irwin Singer,Solomon Scott,et al.

2001160 citations

The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy.

Irwin Singer,S Scott,et al.

1995154 citations

Interleukin 1 beta is localized in the cytoplasmic ground substance but is largely absent from the Golgi apparatus and plasma membranes of stimulated human monocytes.

Irwin Singer,S Scott,et al.

1988148 citations

Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Erik Lund,Laurence B. Peterson,et al.

2005144 citations

A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]

Ni Yan,Stefania Di Marco,et al.

2010133 citations