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Defining the Role of mTOR in Cancer

20072,803 citationsReviewbronze Open Access

Authors

David A. Guertin · Whitehead Institute for Biomedical Research

David M. Sabatini · Massachusetts Institute of Technology

Topics & Keywords

PI3K/AKT/mTOR signaling in cancer Polyamine Metabolism and Applications Protein Kinase Regulation and GTPase Signaling

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Cell

Volume 12, Issue 1, pp. 9-22

DOI: 10.1016/j.ccr.2007.05.008

Field-Weighted Citation Impact: 74.39

Defining the Role of mTOR in Cancer | Researchclopedia