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David M. Sabatini | Researchclopedia

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David M. Sabatini

Czech Academy of Sciences ORCID

531

Works

154,373

Citations

149

h-index

279

i10-index

Research Topics

PI3K/AKT/mTOR signaling in cancer Protein Kinase Regulation and GTPase Signaling CRISPR and Genetic Engineering

Affiliations

Broad Institute2006–2023

Scripps Research Institute2010–2010

Brigham and Women's Hospital2013–2014

Mount Sinai Hospital2013–2013

Albert Einstein College of Medicine1990–1990

Top Works

mTOR Signaling in Growth Control and Disease

Mathieu Laplante,David M. Sabatini

20128,380 citations

Cancer, Hypoxia, and Metabolism

Polyamine Metabolism and Applications

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton,David M. Sabatini

20177,271 citations

Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov,David A. Guertin,et al.

20056,148 citations

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter,Thouis R. Jones,et al.

20065,413 citations

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie,Pablo Tamayo,et al.

20094,120 citations

mTOR: from growth signal integration to cancer, diabetes and ageing

Roberto Zoncu,Alejo Efeyan,et al.

20103,931 citations

mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

Do‐Hyung Kim,Dos D. Sarbassov,et al.

20022,961 citations

Defining the Role of mTOR in Cancer

David A. Guertin,David M. Sabatini

20072,803 citations

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak,Timothy R. Peterson,et al.

20082,746 citations