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Crypt stem cells as the cells-of-origin of intestinal cancer

20082,142 citationsJournal Article

Authors

Nick Barker · Hubrecht Institute for Developmental Biology and Stem Cell Research

Rachel A. Ridgway · Cancer Research UK Scotland Institute

Johan H. van Es · Hubrecht Institute for Developmental Biology and Stem Cell Research

Marc van de Wetering · Hubrecht Institute for Developmental Biology and Stem Cell Research

Harry Begthel · Hubrecht Institute for Developmental Biology and Stem Cell Research

Maaike van den Born · Hubrecht Institute for Developmental Biology and Stem Cell Research

Topics & Keywords

Cancer Cells and Metastasis Wnt/β-catenin signaling in development and cancer Genetic factors in colorectal cancer

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Nature

Volume 457, Issue 7229, pp. 608-611

DOI: 10.1038/nature07602

Field-Weighted Citation Impact: 51.30

Crypt stem cells as the cells-of-origin of intestinal cancer | Researchclopedia

Esther Danenberg · Hubrecht Institute for Developmental Biology and Stem Cell Research

Alan R. Clarke · Cardiff University

Owen J. Sansom · Cancer Research UK Scotland Institute

Hans Clevers · Hubrecht Institute for Developmental Biology and Stem Cell Research