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Johan H. van Es | Researchclopedia

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Johan H. van Es

Royal Netherlands Academy of Arts and Sciences ORCID

197

Works

56,334

Citations

77

h-index

123

i10-index

Research Topics

Cancer Cells and Metastasis Wnt/β-catenin signaling in development and cancer Digestive system and related health

Affiliations

Royal Netherlands Academy of Arts and Sciences2010–2026

Howard Hughes Medical Institute1989–1989

Utrecht University1964–2023

Liverpool School of Tropical Medicine2014–2014

Heidelberg University1992–1992

Top Works

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato,Robert G.J. Vries,et al.

20097,010 citations

Venous Thromboembolism Diagnosis and Management

Cancer Research and Treatments

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker,Johan H. van Es,et al.

20075,633 citations

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

Toshiro Sato,Daniel E. Stange,et al.

20113,714 citations

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

Toshiro Sato,Johan H. van Es,et al.

20102,448 citations

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker,Rachel A. Ridgway,et al.

20082,142 citations

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

Hugo J.G. Snippert,Laurens G. van der Flier,et al.

20101,953 citations

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

Meritxell Huch,Craig Dorrell,et al.

20131,562 citations

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker,Meritxell Huch,et al.

20101,532 citations

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Johan H. van Es,Mariëlle van Gijn,et al.

20051,510 citations