Purified Anthocyanin Supplementation Improves Endothelial Function via NO-cGMP Activation in Hypercholesterolemic Individuals

2011220 citationsJournal Articlebronze Open Access

Authors

Yanna Zhu · State Key Laboratory of Food Science and Technology

Min Xia · State Key Laboratory of Food Science and Technology

Yan Yang · State Key Laboratory of Food Science and Technology

Fengqiong Liu · State Key Laboratory of Food Science and Technology

Zhongxia Li · State Key Laboratory of Food Science and Technology

Yuantao Hao · State Key Laboratory of Food Science and Technology

Abstract

Anthocyanin supplementation improves endothelium-dependent vasodilation in hypercholesterolemic individuals. This effect involves activation of the NO-cGMP signaling pathway, improvements in the serum lipid profile, and decreased inflammation.

Topics & Keywords

Phytochemicals and Antioxidant Activities Atherosclerosis and Cardiovascular Diseases Antioxidant Activity and Oxidative Stress

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 57, Issue 11, pp. 1524-1533

DOI: 10.1373/clinchem.2011.167361

Field-Weighted Citation Impact: 5.11