Increasing Failure of Miltefosine in the Treatment of Kala-azar in Nepal and the Potential Role of Parasite Drug Resistance, Reinfection, or Noncompliance

2013315 citationsJournal Articlebronze Open Access

Authors

Suman Rijal · B.P. Koirala Institute of Health Sciences

Bart Ostyn · Instituut voor Tropische Geneeskunde

Surendra Uranw · B.P. Koirala Institute of Health Sciences

Keshav Rai · B.P. Koirala Institute of Health Sciences

Narayan Raj Bhattarai · B.P. Koirala Institute of Health Sciences

Thomas P. C. Dorlo · Utrecht University

Jos H. Beijnen

Abstract

Relapse in one-fifth of the MIL-treated patients observed in our study is an alarming signal for the VL elimination campaign, urging for further review and cohort monitoring.

Topics & Keywords

Research on Leishmaniasis Studies Parasites and Host Interactions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 56, Issue 11, pp. 1530-1538

DOI: 10.1093/cid/cit102

Field-Weighted Citation Impact: 31.63