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Jos H. Beijnen | Researchclopedia

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Jos H. Beijnen

University of Applied Sciences Utrecht ORCID

1,778

Works

75,323

Citations

129

h-index

1118

i10-index

Research Topics

Drug Transport and Resistance Mechanisms Cancer Treatment and Pharmacology Cancer therapeutics and mechanisms

Affiliations

Kanazawa University2014–2014

AstraZeneca (United Kingdom)2006–2006

Leiden University1995–1995

University of Iowa2005–2005

European Organisation for Research and Treatment of Cancer1994–1995

Top Works

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel,Jasper Smit,et al.

19942,272 citations

Pharmacogenetics and Drug Metabolism

Colorectal Cancer Treatments and Studies

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom,Judith van Asperen,et al.

1997878 citations

A Phase I and Pharmacological Study with Imidazolium-<b> <i>trans-</i> </b>DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Jeany M. Rademaker-Lakhai,H.J.G.D. van den Bongard,et al.

2004820 citations

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Johan W. Jonker,Marije Buitelaar,et al.

2002818 citations

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Thomas P. C. Dorlo,Manica Balasegaram,et al.

2012753 citations

Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Ron J. Keizer,Alwin D. R. Huitema,et al.

2010703 citations

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

Ellen Stokvis,Hilde Rosing,et al.

2005568 citations

An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

Esther Brandon,Christiaan D Raap,et al.

2003555 citations

Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors

Kimberley M. Heinhuis,Willeke Ros,et al.

2019551 citations