VLDL lipidomics reveals hepatocellular lipidome changes in metabolic dysfunction–associated steatotic liver disease

20252 citationsJournal Articlegold Open Access

Authors

David Guardamino Ojeda · Beth Israel Deaconess Medical Center

Yusuf Yalcin · Tufts University

Yered Pita-Juárez · Harvard University

Aaron Hakim · Harvard University

Susmita Bhattarai · Harvard University

Zsu‐Zsu Chen · Harvard University

John M. Asara ·

Abstract

Hepatic steatosis and liver fibrosis in MASLD are associated with distinct VLDL-lipidomic signatures, respectively. This relationship is further modified by MASLD-genetics, suggesting a differential impact of pathogenic features on hepatocellular lipid homeostasis.

Topics & Keywords

Liver Disease Diagnosis and Treatment Diet, Metabolism, and Disease Lipid metabolism and biosynthesis

Publication Details

Published in: Hepatology Communications

Volume 9, Issue 6

DOI: 10.1097/hc9.0000000000000716

Field-Weighted Citation Impact: 2.84

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VLDL lipidomics reveals hepatocellular lipidome changes in metabolic dysfunction–associated steatotic liver disease

Authors

Abstract

Topics & Keywords

Publication Details