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John M. Asara | Researchclopedia

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John M. Asara

Beth Israel Deaconess Medical Center ORCID

833

Works

60,596

Citations

115

h-index

313

i10-index

Research Topics

Cancer, Hypoxia, and Metabolism RNA modifications and cancer Epigenetics and DNA Methylation

Affiliations

Broad Institute2012–2013

Dartmouth College2003–2003

Boston University2008–2020

University of North Carolina at Chapel Hill2020–2020

Brigham and Women's Hospital2012–2013

Top Works

HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O <sub>2</sub> Sensing

Mircea Ivan,Keiichi Kondo,et al.

20014,661 citations

Lung Cancer Treatments and Mutations

PI3K/AKT/mTOR signaling in cancer

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan,David B. Shackelford,et al.

20102,528 citations

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

Haoqiang Ying,Alec C. Kimmelman,et al.

20122,006 citations

Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

Jaekyoung Son,Costas A. Lyssiotis,et al.

20131,942 citations

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

Valerie S. LeBleu,Joyce T. O’Connell,et al.

20141,389 citations

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

Andrea Viale,Piergiorgio Pettazzoni,et al.

20141,216 citations

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

Dimitrios Anastasiou,George Poulogiannis,et al.

20111,173 citations

A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue

Min Yuan,Susanne B. Breitkopf,et al.

20121,139 citations

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale,Alexandra Grassian,et al.

20111,114 citations