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W. Alderton | Researchclopedia

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W. Alderton

47

Works

8,329

Citations

17

h-index

21

i10-index

Research Topics

Nitric Oxide and Endothelin Effects Zebrafish Biomedical Research Applications Receptor Mechanisms and Signaling

Affiliations

University of Essex2000–2000

University of Hertfordshire1999–1999

Institute of Cancer Research2008–2008

GlaxoSmithKline (United Kingdom)2001–2011

Pfizer (United Kingdom)2008–2008

Top Works

Nitric oxide synthases: structure, function and inhibition

W. Alderton,Chris E. Cooper,et al.

20013,545 citations

Cardiac electrophysiology and arrhythmias

Metal-Catalyzed Oxygenation Mechanisms

Nitric oxide synthases: structure, function and inhibition

W. Alderton,Chris E. Cooper,et al.

20012,661 citations

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Adrian Folkes,Khatereh Ahmadi,et al.

2008741 citations

Zebrafish: an emerging technology for <i>in vivo</i> pharmacological assessment to identify potential safety liabilities in early drug discovery

Teresa P. Barros,W. Alderton,et al.

2008271 citations

Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery

Stéphane Berghmans,Paul Butler,et al.

2008187 citations

Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples

Darren Thomas,E‐O Fourkala,et al.

2015131 citations

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae

W. Alderton,Stéphane Berghmans,et al.

2010109 citations

Designer dyes: ‘biomimetic’ ligands for the purification of pharmaceutical proteins by affinity chromatography

Christopher R. Lowe,Steven J. Burton,et al.

1992105 citations

Validation of the use of zebrafish larvae in visual safety assessment

Frances M. Richards,W. Alderton,et al.

200889 citations