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Iakov N. Rudenko | Researchclopedia

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Iakov N. Rudenko

Central Clinical Hospital

17

Works

1,392

Citations

14

h-index

14

i10-index

Research Topics

Parkinson's Disease Mechanisms and Treatments Plant Gene Expression Analysis Neurological diseases and metabolism

Affiliations

National Institutes of Health2012–2018

Russian Academy of Sciences2010–2010

Stony Brook School2018–2018

Cell and Gene Therapy Catapult2013–2014

Stony Brook Medicine2018–2018

Top Works

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Alexandria Beilina,Iakov N. Rudenko,et al.

2014363 citations

Ubiquitin and proteasome pathways

Banana Cultivation and Research

Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation

Guoxiang Liu,Jia Yu,et al.

2014162 citations

mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex

Allissa Dillman,David N. Hauser,et al.

2013158 citations

The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation

Iakov N. Rudenko,Alice Kaganovich,et al.

2012118 citations

Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7

Ruth Chia,Sara Haddock,et al.

2014102 citations

Hexokinase activity is required for recruitment of parkin to depolarized mitochondria

Melissa K. McCoy,Alice Kaganovich,et al.

201397 citations

Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle

Evy Lobbestael,Jing Zhao,et al.

201394 citations

Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice

Laura Pellegrini,David N. Hauser,et al.

201866 citations

Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease?

Iakov N. Rudenko,Ruth Chia,et al.

201264 citations