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Anna‐Leigh Brown | Researchclopedia

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Anna‐Leigh Brown

Queen Mary University of London

17

Works

1,245

Citations

11

h-index

11

i10-index

Research Topics

Amyotrophic Lateral Sclerosis Research RNA Research and Splicing Neurogenetic and Muscular Disorders Research

Affiliations

National Institutes of Health2019–2019

Queen Mary University of London2025–2025

Constructor University2018–2018

United States National Library of Medicine2019–2019

National Center for Biotechnology Information2019–2021

Top Works

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna‐Leigh Brown,Oscar G. Wilkins,et al.

2022486 citations

Lung Cancer Treatments and Mutations

Genetic Neurodegenerative Diseases

Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer

Nitin Roper,Anna‐Leigh Brown,et al.

2020175 citations

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Nitin Roper,Moises J. Velez,et al.

2021157 citations

The era of cryptic exons: implications for ALS-FTD

Puja R. Mehta,Anna‐Leigh Brown,et al.

2023138 citations

APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors

Nitin Roper,Shaojian Gao,et al.

2019107 citations

Cell environment shapes TDP-43 function with implications in neuronal and muscle disease

Urša Šušnjar,Neva Škrabar,et al.

202250 citations

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing

Alexander Bampton,Ariana Gatt,et al.

202147 citations

Unexpected frequency of the pathogenic <i>AR</i> CAG repeat expansion in the general population

Matteo Zanovello,Kristina Ibáñez,et al.

202328 citations

Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization

Anna‐Leigh Brown,Oscar G. Wilkins,et al.

202118 citations