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Burkhard Jakob | Researchclopedia

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Burkhard Jakob

GSI Helmholtz Centre for Heavy Ion Research ORCID

83

Works

3,619

Citations

34

h-index

49

i10-index

Research Topics

DNA Repair Mechanisms Radiation Therapy and Dosimetry Carcinogens and Genotoxicity Assessment

Affiliations

University of Debrecen2016–2016

GSI Helmholtz Centre for Heavy Ion Research2001–2025

Friedrich-Alexander-Universität Erlangen-Nürnberg2006–2009

University of Würzburg1996–1999

Laboratoire de physique des Solides2022–2022

Top Works

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

Naoya Uematsu,Eric Weterings,et al.

2007402 citations

PARP inhibition in cancer therapy

Genomics and Chromatin Dynamics

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

Burkhard Jakob,J. Splinter,et al.

2011306 citations

Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization

Sylvain V. Costes,Irene Chiolo,et al.

2010205 citations

Autophosphorylation and ATM Activation

Sergei Kozlov,Mark E. Graham,et al.

2010194 citations

Live cell microscopy analysis of radiation-induced DNA double-strand break motion

Burkhard Jakob,J. Splinter,et al.

2009180 citations

Biological Imaging of Heavy Charged-Particle Tracks

Burkhard Jakob,M. Scholz,et al.

2003158 citations

Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA–PK

Bernhard Meyer,Kay‐Obbe Voss,et al.

2013115 citations

Nanoscale analysis of clustered DNA damage after high-LET irradiation by quantitative electron microscopy – The heavy burden to repair

Yvonne Lorat,Christina U. Brunner,et al.

2015109 citations

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase

Kyung Jong Lee,Janapriya Saha,et al.

2015101 citations