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Derek P. Narendra | Researchclopedia

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Derek P. Narendra

National Institutes of Health ORCID

78

Works

30,607

Citations

29

h-index

40

i10-index

Research Topics

Autophagy in Disease and Therapy Parkinson's Disease Mechanisms and Treatments Mitochondrial Function and Pathology

Affiliations

Brigham and Women's Hospital2014–2017

National Institutes of Health2008–2026

Howard Hughes Medical Institute2008–2008

Johns Hopkins University2004–2005

Queen Mary University of London2019–2019

Top Works

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra,Atsushi Tanaka,et al.

20083,927 citations

Genetic Neurodegenerative Diseases

ATP Synthase and ATPases Research

Mechanisms of mitophagy

Richard J. Youle,Derek P. Narendra

20103,159 citations

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra,Seok Min Jin,et al.

20102,862 citations

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

Atsushi Tanaka,Megan M. Cleland,et al.

20101,330 citations

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

Seok Min Jin,Michael Lazarou,et al.

20101,323 citations

RETRACTED ARTICLE: Parkin and PINK1 mitigate STING-induced inflammation

Danielle A. Sliter,Jennifer Martinez,et al.

20181,312 citations

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

Derek P. Narendra,Lesley A. Kane,et al.

2010778 citations

Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to Therapy

Ana Belén Malpartida,Matthew G Williamson,et al.

2020449 citations

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

Derek P. Narendra,Richard J. Youle

2011360 citations