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Karl Normington | Researchclopedia

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Karl Normington

18

Works

3,460

Citations

12

h-index

13

i10-index

Research Topics

Endoplasmic Reticulum Stress and Disease Glycosylation and Glycoproteins Research Pancreatic function and diabetes

Affiliations

Bee Research Institute1997–1997

The University of Texas Southwestern Medical Center1988–1993

Top Works

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

Yasunori Kozutsumi,Mark S. Segal,et al.

19881,303 citations

Fungal and yeast genetics research

Metabolism, Diabetes, and Cancer

S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

Karl Normington,Kenji Kohno,et al.

1989416 citations

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions.

Karl Normington,David W. Russell

1992376 citations

A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

Kazutoshi Mori,Andrea J. Sant,et al.

1992372 citations

The Promoter Region of the Yeast <i>KAR2</i> (BiP) Gene Contains a Regulatory Domain that Responds to the Presence of Unfolded Proteins in the Endoplasmic Reticulum

Kenji Kohno,Karl Normington,et al.

1993323 citations

Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade

Michal A. Stanczak,Natália Rodrigues Mantuano,et al.

2022207 citations

Characterization and chromosomal mapping of a human steroid 5α-reductase gene and pseudogene and mapping of the mouse homologue

Elizabeth P. Jenkins,Chih-Lin Hsieh,et al.

1991152 citations

Novel Insulinoma Cell Lines Produced by Iterative Engineering of GLUT2, Glucokinase, and Human Insulin Expression

Sam Clark,C Quaade,et al.

199779 citations

Engineered cell lines for insulin replacement in diabetes: current status and future prospects

Christopher B. Newgard,Sam Clark,et al.

199766 citations