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Gernot Kleinberger | Researchclopedia

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Gernot Kleinberger

Munich Cluster for Systems Neurology ORCID

85

Works

8,011

Citations

35

h-index

45

i10-index

Research Topics

Neuroinflammation and Neurodegeneration Mechanisms Inflammation biomarkers and pathways Alzheimer's disease research and treatments

Affiliations

University of Antwerp2008–2015

Washington University in St. Louis2018–2018

German Center for Neurodegenerative Diseases2013–2022

LMU Klinikum2020–2020

Bioscience Research2019–2019

Top Works

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

Gernot Kleinberger,Yoshinori Yamanishi,et al.

2014823 citations

Amyotrophic Lateral Sclerosis Research

Neurological Disease Mechanisms and Treatments

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study

Ilse Gijselinck,Tim Van Langenhove,et al.

2011627 citations

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

Hans Wils,Gernot Kleinberger,et al.

2010595 citations

<scp>sTREM</scp> 2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

Marc Suárez‐Calvet,Gernot Kleinberger,et al.

2016517 citations

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

for the Alzheimer’s Disease Neuroimaging Initiative,Marc Suárez‐Calvet,et al.

2019369 citations

Enhancing protective microglial activities with a dual function <scp>TREM</scp> 2 antibody to the stalk region

Kai Schlepckow,Kathryn M. Monroe,et al.

2020349 citations

<scp>TREM</scp> 2 deficiency impairs chemotaxis and microglial responses to neuronal injury

Fargol Mazaheri,Nicolas Snaidero,et al.

2017346 citations

hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations

Kohji Mori,Sven Lammich,et al.

2013344 citations

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease

Michael Ewers,Nicolai Franzmeier,et al.

2019326 citations